The widespread use of dried blood in neonatal screenings for metabolic diseases has proven the viability of this sample material. Henceforth its application in drug screenings, doping tests and therapeutic drug monitoring is increasingly taken into consideration.
Sample collection is minimally invasive and requires less effort by the sample collecting staff than venous blood sampling and the patients privacy is just as well protected as in saliva sampling. No special education is necessary to conduct the sample collection. Dried blood extracted from the fingertip can be a welcome alternative if venous access is obstructed.
Some drugs (e. g. cocaine) are stabilized by the drying process. The low sample volume is advantageous when storing samples.
The disadvantage is that only a very small sample volume is available for the analysis and that in quantitative concentration data the hematocrit of the sample must be taken into account.