Sample Collection: Dried Blood Samples (DBS)

The widespread use of dried blood in neonatal screenings for metabolic diseases has proven the viability of this sample material. Henceforth its application in drug screenings, doping tests and therapeutic drug monitoring is increasingly taken into consideration.

Sample collection is minimally invasive and requires less effort by the sample collecting staff than venous blood sampling and the patients privacy is just as well protected as in saliva sampling. No special education is necessary to conduct the sample collection. Dried blood extracted from the fingertip can be a welcome alternative if venous access is obstructed.

Some drugs (e. g. cocaine) are stabilized by the drying process. The low sample volume is advantageous when storing samples.

The disadvantage is that only a very small sample volume is available for the analysis and that in quantitative concentration data the hematocrit of the sample must be taken into account.

Further information on relevant topics

Blood/Serum

Blood/Serum

For a test of alcohol, of the alcohol marker ethylglucuronide, of CDT or the liver values (AST, ALT, GGT) the blood sample should be taken by medical staff.

Meconium

Meconium

Please send meconium samples immediately after collection to the lab. Drugs are stable in frozen samples (-15 °C) for up to nine months.

Urine

Urine

To prevent adulteration, collection of a forensic urine sample should occur under supervision. We recommend the collection in a urine cup from which a few mL are transferred into a urine Monovette®

Hair

Hair

The collection of a hair sample for an analysis of drugs of abuse, medical drugs or the alcohol marker ethylglucuronide is not a medical intervention. Hence it must not be carried out by medical staff. However, it should be performed by qualified trained persons according to recognized guidelines to avoid pre-analytical errors.

Saliva

Saliva

The collection of a saliva sample for an analysis of drugs of abuse or medical drugs is not a medical intervention. Hence it must not be carried out by medical staff. However, it should be performed by qualified trained persons according to recognized guidelines to avoid pre-analytical errors.

Storage

Storage

If transport to our laboratory is delayed, depending on sample material, certain aspects have to be noted.

Transport

Transport

Besides postage a shipment of samples by courier is possible within most parts of Germany.

ILAC-MRA
DAKKS
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